2017/2018

2017/2018

DM270

CHIM/03 (GENERAL AND INORGANIC CHEMISTRY)

DEPARTMENT OF DRUGS SCIENCES

MEDICINAL CHEMISTRY AND PHARMACEUTICAL TECHNOLOGY

PERCORSO COMUNE

1°

1st semester (02/10/2017 - 31/01/2018)

9

72 lesson hours

Italian

WRITTEN TEST

MARINI AMEDEO (titolare) - 9 ECTS

Secondary school level mathematics and physics.

The aim of the course is to give to the students the basic chemistry knowledge needed to understand the subsequent
specialized courses. The basic principles (moles, pH, solution equilibriums) are thoroughly discussed also by using
stoichiometric calculations with the aim to consolidate the understanding of the basic principles and to make the students
able to tackle chemical issues by a rational approach. Inorganic chemistry topics are spread all over the course with the
double aim to introduce and to apply general concepts.
At the end of the course, students will have the knowledge, the expertise and the working method needed to follow fruitfully the subsequent chemical teachings of their study course.

Basics. Atoms and molecules. Atomic mass scale. Atomic mass unit. Atomic number, mass number, isotopes. Periodic table and periodic properties. Shell model, octet rule and chemical bonds. Valence, chemical formula and chemical nomenclature. Gases study: pressure and its measurement. Ideal and real gases. Electronegativity. Ionic and covalent bonds. Oxidation state and oxidation numbers. Redox reactions. Solutions and solution equilibriums: Bronsted and Lowry theory of acids and bases. Weak acids and bases: equilibrium and equilibrium constant. pH scale. pH calculation in solution containing strong or weak acids and bases. Acids-bases reactions, buffer solutions, ampholitic species. Mixtures of acids, bases and acids plus bases. Acid-bases titrations and indicators. Solutions, solubility and solubility product. Atomic Structure, Chemical Properties and Chemical Bonds: atomic spectra and energy quantization, ionization energy, energetic levels, electronic configurations and chemical bonds. Lewis structural formulas, resonance and resonance hybrids. Hybrid orbitals and molecular geometry. Structure of metals, metallic bond and metallic properties. Lewis theory of acids and bases. Atomic structure insights: the Thomson atomic model, the Rutherford atomic model. Planck quantum theory. The hydrogen spectrum. The Bohr atomic model. Energy quantization, matter and waves. The Heisemberg uncertainty principle.
Inorganic Chemistry: Sources, uses and chemical properties of selected elements (nitrogen, oxygen, fluorine, chlorine, bromine, iodine, phosphorus, sulfur, aluminum, copper, iron, lead) are deeply discussed to introduce and apply relevant general chemistry concepts.

Lectures with power point slides.
Students are encouraged to interact each other and with the professor in the lecture room and with tutors by Kiro platform.
Stoichiometry based exercises will be part of the course. They are solved by professor-students interaction. Their aim is to reinforce and deepen the understanding of the basic principles by their application.
Students will also be supported by tutors.

Lectures notes provided by the teacher in digital form on Kiro platform. It is also suggested a university level reference book.

One in itinere test is envisaged in the middle of the course. It has two aims: 1) to encourage students to study during the course rather than after the course; 2) to give the students the way to verify their learning level by a non-punitive mid-course test. Such a mid-course test contributes to the final evaluation only for students which substained it successfully.
The final exam, as well as the mid term one, is based on a written test consisting of five open-ended questions and five exercises.
The first ones are aimed at evaluating both the quantity and quality of the learning, in particular by assessing the student ability to correctly identify the object of the questions and to give all the elements useful to formulate a clear answer and to make it understandable.
The secon ones serve to verify that students are able to apply their theoretical knowledge to the solution of real problems.
The final exam is passed if students show to know and to be able to apply an adequate share of the knowledge and skills provided by thr course.

One in itinere test is envisaged in the middle of the course. It has two aims: 1) to encourage students to study during the course rather than after the course; 2) to give the students the way to verify their learning level by a non-punitive mid-course test. Such a mid-course test contributes to the final evaluation only for students which substained it successfully.
The final exam, as well as the mid term one, is based on a written test consisting of five open-ended questions and five exercises.
The first ones are aimed at evaluating both the quantity and quality of the learning, in particular by assessing the student ability to correctly identify the object of the questions and to give all the elements useful to formulate a clear answer and to make it understandable.
The secon ones serve to verify that students are able to apply their theoretical knowledge to the solution of real problems.
The final exam is passed if students show to know and to be able to apply an adequate share of the knowledge and skills provided by thr course.