DEPARTMENT OF BIOLOGY AND BIOTECHNOLOGY "LAZZARO SPALLANZANI"
48 lesson hours
Basic knowledge of the structure of biological macromolecules and of the function of the main cell organelles.
To stimulate the study of the cell substructures from morphological, functional and molecular prospective with constant recall of the chemical processes involved. To provide students know-how and reasoning strategies for identifying potential subjects for the development of biotechnological applications.
Biological macromolecules: proteins, nucleic acids, carbohydrates, lipids. Role of covalent and non-covalent bonds for macromolecule structure. Structure and function of cellular structures: plasma membrane, endomembrane system (rough and smooth endoplasmic reticulum, ribosomes, Golgi apparatus, endocytosis and exocytosis, lysosomes). Anaerobic and aerobic metabolism: glycolysis, mitochondria, peroxisomes. Cytoskeleton and cell motility (microfilaments, microtubules, intermediate filaments). Eukaryotic cell nucleus (nuclear envelope, nuclear lamina, nuclear pores, chromatin, nucleolus). Cell reproduction (mitosis, meiosis). Elements of Histology.
Lectures carried out through ppt presentations. The PDFs of the slides will be uploaded to kiro (https://idcd.unipv.it/kiro3/) and available to students. Practical lesson could be organized focused at acquiring basic skills in the use of the optical microscope and the observation of histological and cellular preparations.
Reccomended or required readings
Colombo e Olmo: BIOLOGIA -CELLULA E TESSUTI. EdiErmes
The exam will be written. The questions include the full program topics and are organized as followed:
- three true or false questions (maximum score 2 points/each);
- three short answer questions (maximum length of answer: 5 lines) and maximum score: 2 points/each;
- two open questions (maximum length of answer: 15 lines). Maximum score: 5 points/each;
- one open question (maximum length of answer: 30 lines). Maximum score: 10 points/each.
The exam will be passed with a score equal or greater than 18/30. The maximum score is 30/30 cum laude (which will be assigned when the score is greater than 30).