CLINICAL PATHOLOGY AND IMMUNOLOGY
Stampa
Enrollment year
2021/2022
Academic year
2021/2022
Regulations
DM270
Academic discipline
MED/04 (GENERAL PATHOLOGY)
Department
DEPARTMENT OF BIOLOGY AND BIOTECHNOLOGY "LAZZARO SPALLANZANI"
Course
EXPERIMENTAL AND APPLIED BIOLOGY
Curriculum
Bioanalisi
Year of study
Period
2nd semester (01/03/2022 - 14/06/2022)
ECTS
6
Lesson hours
48 lesson hours
Language
Italian
Activity type
WRITTEN TEST
Teacher
SCOTTI CLAUDIA (titolare) - 3 ECTS
FERRAROTTI ILARIA - 3 ECTS
Prerequisites
Useful background knowledge comes from the contents of the course of General Pathology, particularly cellular pathology, inflammation and tumours. Basis of chemistry, physioogy and human anatomy are useful to follow the course, but for each chapter key information from other subjects is preliminarly revised.
Learning outcomes
The objective of the course is to introduce students to the integrated structure of a Clinical Pathology laboratory, analysing the chapters which are not covered by other courses and giving the student a through view of the field.
Course contents
Introductory overview on the functioning of the immune system
Receptor repertoire of immune cells, cytokines, immunoglobulins, chemokines; production of antibodies, monoclonal antibodies, polyclonal antibodies.
The laboratory methodologies of the immunologist: isolation, cultivation and characterization of cells of the immune system; methods of immunization; detection and characterization of antibodies and their use in research and diagnostics; serological assays, affinity chromatography, radioimmunoassays, immunoenzymatic assays, competitive inhibition, hemagglutination, immunoprecipitation, cytotoxicity, neutralization; flow cytometry, tissue typing methods, functional assays; examples of laboratory diagnostics of some autoimmune diseases.
The transfusion laboratory; the HLA laboratory
Teaching methods
Lectures
Reccomended or required readings
Kiro website, with extra material and links to deepen the knowledge.
Assessment methods
Written exam, with three questions in the form of short assays.
Further information
Written exam, with three questions in the form of short assays.
Sustainable development goals - Agenda 2030