2020/2021

2021/2022

DM270

CHIM/03 (GENERAL AND INORGANIC CHEMISTRY)

DEPARTMENT OF BIOLOGY AND BIOTECHNOLOGY "LAZZARO SPALLANZANI"

BIOTECHNOLOGY

PERCORSO COMUNE

2°

(01/10/2021 - 14/01/2022)

3

24 lesson hours

Italian

ORAL TEST

PORTA ALESSIO (titolare) - 3 ECTS

None

The aim of the course is the teaching of the applications of the NMR
technique for the characterization of molecules of biotechnological
interest, starting from the study on small organic molecules up to the
analysis of proteins

The NMR module deals with the basic principles of the nuclear magnetic
resonance. After a brief reference to the physical aspects of technique,
the origin of signals in the spectrum and their use for the structure
determination of low molecular weight molecules, in particular those of
biochemical interest, will be shown. The multidimensional techniques will
be briefly treated, showing their applications. The last part of the module
will show the use of NMR for the determination of protein structures in
solution

The course includes (optional) practical exercises on an instrument

Lecture notes in PDF format

The course requires passing a written examination on spectra interpretation, simulation and on the theory

None