TOXICOLOGY AND SAFETY OF BIOTECHNOLOGY PRODUCTS
Stampa
Enrollment year
2020/2021
Academic year
2020/2021
Regulations
DM270
Academic discipline
BIO/14 (PHARMACOLOGY)
Department
DEPARTMENT OF BIOLOGY AND BIOTECHNOLOGY "LAZZARO SPALLANZANI"
Course
ADVANCED BIOTECHNOLOGY
Curriculum
PERCORSO COMUNE
Year of study
Period
2nd semester (01/03/2021 - 14/06/2021)
ECTS
6
Lesson hours
48 lesson hours
Language
Italian
Activity type
ORAL TEST
Teacher
DOSSENA MAURIZIA (titolare) - 3 ECTS
VERRI MANUELA - 3 ECTS
Prerequisites
None
Learning outcomes
The course aims to describe the nature and mechanisms that characterize the adverse effects related to different biotechnology-derived products: biological medicinal products, diagnostic products, cosmetics and food supplements.
Course contents
Principles of general toxicology: major areas of toxicology; toxic agents; exposure characteristics; classification of adverse effects; dose-response relationship; threshold effects; mechanisms of toxicity; toxicokinetics; risk assessment. Toxicology in drug development phases. Biotechnology-derived products: general aspects. Toxicology of biotechnology-derived medicinal products: monoclonal antibodies; cytokines and growth factors; blood derivatives; recombinant enzymes and hormones; recombinant vaccines; biosimilars. Biotechnology and food safety. Genetically modified organisms. Toxicology of cosmetics. Biotechnology and sustainable development.
Teaching methods
Lessons and seminars
Reccomended or required readings
Slides
Casarett & Doull's
"Toxicology" Ed.Ambrosianaes
Assessment methods
Oral exam
Further information
Sustainable development goals - Agenda 2030