2019/2020

2019/2020

DM270

MED/04 (GENERAL PATHOLOGY)

DEPARTMENT OF MOLECULAR MEDICINE

MEDICAL AND PHARMACEUTICAL TECHNOLOGIES

PERCORSO COMUNE

1°

2nd semester (02/03/2020 - 29/05/2020)

6

48 lesson hours

Italian

WRITTEN TEST

CAZZALINI ORNELLA (titolare) - 6 ECTS

Knowledge of cytology and histology, biochemistry, anatomy and phisiology. Skills in basic techniques of cellular and molecular biology.

The aim of the course is the acquisition of conceptual and scientific basis to explain both causes and mechanisms of human diseases. In particular, the students at the end of course have to know:

1. the main chemical, physical and biological pathogenic factors and their effects on cells and tissues;

2. general principles underlying disorders of integrity and identity and biological features of the complex systems.

3. reactions to the biological damage that are crucial in the process of healing/repair or disease progression, with particular attention to the mechanisms of immunity, inflammation, wound healing and chronic disease processes.

4. etiology of the most common genetic diseases, congenital and acquired, with particular reference to the immune system disorders, degenerative diseases of the blood vessels and tumors.

5. scientific terms and specific language used in medicine to facilitate interaction with other researchers in biomedical area.

Introduction to General Pathology

Etiology
External and internal agents to the basis of human diseases.

Dynamics of cell injury
Cell death; Necrosis and apoptosis; pyroptosis; necroptosis; experimental models and methods of study.

- Degeneration and degenerative diseases. Intracellular and extracellular accumulations. Study of molecular and cellular models.

- Acute and chronic inflammation; Chemical mediators; Healing processes; Historical models and recent studies of inflammation.

- Pathological growths. Tumors. Inflammation,Tumor and Immunity connections. Biotechnology in oncology: cellular and molecular approaches.

- Hypersensitivity reactions, immunodeficiencies, autoimmunity.

- Thrombus and Atheroma

Lectures

Robbins e Cotran, Pathologic basis of disease - Elsevier


Majno e Joris - Cells, Tissue and Disease - Oxford Press

Pontieri, Russo, Frati - Patologia generale e Fisiopatologia generale - PICCIN

Parola - Patologia generale - Edises

Stivala e Vannini - Guida allo studio della patologia generale - Print Service

The slides of the lectures will be available in Kiro site.

Written exam composed by open questions and multiple choice.

Written exam composed by open questions and multiple choice.