PHARMACOLOGICAL THERAPY ELEMENTS
Stampa
Enrollment year
2019/2020
Academic year
2021/2022
Regulations
DM270
Academic discipline
BIO/14 (PHARMACOLOGY)
Department
DEPARTMENT OF BIOLOGY AND BIOTECHNOLOGY "LAZZARO SPALLANZANI"
Course
BIOTECHNOLOGY
Curriculum
PERCORSO COMUNE
Year of study
Period
2nd semester (01/03/2022 - 14/06/2022)
ECTS
6
Lesson hours
48 lesson hours
Language
Italian
Activity type
WRITTEN TEST
Teacher
PAOLILLO MAYRA (titolare) - 3 ECTS
AMADIO MARIALAURA - 3 ECTS
Prerequisites
none
Learning outcomes
The aim of the course is to study the types and the clinical use of these molecules.
Course contents
“New pharmacological therapies for cancer”: The development of novel effective chemotherapeutic drugs requires the knowledge of the main principles relative to molecular and cellular pharmacology, allowing to find out appropriate therapeutic targets, that are molecules or pathways relevant for the etiopathogenesis of tumors.
Biology of tumors, preclinical and clinical research for drug discovery and development; protein kinases; membrane receptors and transduction signals; intracellular kinases and cell cycles-related enzymes; apoptosis; main novel targeted therapies; drugs targeting angiogenesis.

“Monoclonal antibodies”: 4 Basic elements on the immune system functions, innate immunity, acquired immunity, humoral immunity and antibodies
production.
Methods to produce monoclonal antibodies, from mouse to human antibodies. Types of monoclonal antibodies in the clinic, targets and limits of the therapies.
Teaching methods
The course is based on lectures provided by the instructor. No practical exams. No in itinere tests.
Reccomended or required readings
The slides of the course will be available on KIRO platform.
Assessment methods
Final written exam at the end of the lessons.
“Monoclonal Antibodies”: The examination consists of both multiple choice tests and open questions.
“New pharmacological therapies for cancer”: The examination consists of both multiple choice tests and open questions on representative drugs/targets treated during teaching sessions. Knowledge of the general context and main features of a given therapeutic target and/or drug, will be required. The use of the appropriate language will be also evaluated.
If the students answer correctly to both multiple choice tests and open questions will get the excellence (31).
Note that the grade of “New pharmacological therapies for cancer” should be registered together with that one of “Monoclonal Antibodies”, as a unitary course on “Pharmacological therapy elements”. The final grade will be equal to the mathematical mean of the two.
Further information
Final written exam at the end of the lessons.
“Monoclonal Antibodies”: The examination consists of both multiple choice tests and open questions.
“New pharmacological therapies for cancer”: The examination consists of both multiple choice tests and open questions on representative drugs/targets treated during teaching sessions. Knowledge of the general context and main features of a given therapeutic target and/or drug, will be required. The use of the appropriate language will be also evaluated.
If the students answer correctly to both multiple choice tests and open questions will get the excellence (31).
Note that the grade of “New pharmacological therapies for cancer” should be registered together with that one of “Monoclonal Antibodies”, as a unitary course on “Pharmacological therapy elements”. The final grade will be equal to the mathematical mean of the two.