NUTRITION BIOCHEMISTRY
Stampa
Enrollment year
2019/2020
Academic year
2021/2022
Regulations
DM270
Academic discipline
BIO/10 (BIOCHEMISTRY)
Department
DEPARTMENT OF BIOLOGY AND BIOTECHNOLOGY "LAZZARO SPALLANZANI"
Course
BIOLOGICAL SCIENCES
Curriculum
PERCORSO COMUNE
Year of study
Period
2nd semester (01/03/2022 - 14/06/2022)
ECTS
6
Lesson hours
48 lesson hours
Language
Italian
Activity type
ORAL TEST
Teacher
TORTI MAURO (titolare) - 3 ECTS
CANOBBIO ILARIA - 3 ECTS
Prerequisites
Detailed knowledge of structural and metabolic biochemistry as learned from the course at the II year
Learning outcomes
Comprehension of essential concepts of nutritional biochemistry and of the metabolism of nutrients
Course contents
Coordinated regulation of metabolism.
Integration of metabolic pathways. Uptake and cellaur distribution of glucose and other nutrients. Metabolic profiles of liver, muscle, adipose tissue, brain. Metabolic adaption under short and prolonged starvation. Metabolism of ethanol. Metabolic syndrome. Obesity. Insulin and diabetes. Molecular mechanisms regulating food intake and body weight. Metabolism of ethanol.

Drug metabolism.
Role of liver in the metabolism of xenobiotics. The cytochrome P450 oxidases. Xenobiotic conjugation. Glutathione. Bilirubin metabolism Metabolism of Fe.

Colesterol and diet.
Cholesterol biosynthesis and regulation. Metabolism of cholesterol and its derivatives Lipid transport in the blood: lipoproteins. LDL and atherosclerosis.

Fat soluble vitamins.
Biological roles of vitamin D in calcium homeostasis and of vitamin K in blood coagulation. Retinol and vitamin A in cell differentiation and phototrasduction. Anti-oxidant properties of vitamin E.

Water-soluble vitamins.
Natural sources, daily requirements and biological roles

Micronutrients.
The importance and biological role of Iodine, Zinc, Copper, Selenium, Fluoride

Special topics in Nutritional Biochemistry.
Diet and exercise. Diet and pathological conditions, Mediteranean Diet, the ketogenic diet
Teaching methods
frontal lesson
Reccomended or required readings
Nelson DL, COX, MM : I Principi di Biochimica di Lehninger, Zanichelli;
Berg JM, Tymoczko JL, Stryer L: Biochimica, Zanichelli;
Campbell, Farrell: Biochimica, Edises,
Alberts et al: Biologia Molecolare della Cellula, Zanichelli
Murray et al: Harper Biochimica, McGraw
Leuzzi et al Biochimica della Nutrizione, Zanichelli
Arienti, Le Basi Molecolari della Nutrizione, Piccin
Assessment methods
verbal exam
Further information
Sustainable development goals - Agenda 2030