Enrollment year
2018/2019
Department
DEPARTMENT OF MOLECULAR MEDICINE
Course
BIOMEDICAL LABORATORY TECHNIQUES
Curriculum
PERCORSO COMUNE
Period
1st semester (01/10/2020 - 22/01/2021)
Learning outcomes
Two main topics will be discussed.
The first deals with the role of the laboratory in the clinical workup of patients, as well as in the assessment of health status. The students will know the biochemical and molecular tools needed to accomplish preventive, diagnostic, and therapeutic intervention on hereditary and acquired disorders.
The second topics deals with the knowledge of the theory and lab bases useful for the correct implementation of forensic toxicological and genetic analyses dealing with the search of volatile and non-volatile organic compounds in biological samples and with the genetic characterisation of biological stains and paternity testing samples
Course contents
The course is aimed to describe the molecular diagnostic and the forensic toxicological and genetic lab approaches.
At the end of the class, students shall prove to be able to deal with pre-analytical variables, the assessment of the diagnostic performance of laboratory tests according to the clinical setting and with the molecular diagnostics in monoclonal gammapathies, cardiology, nephrology and oncology.
The forensic toxicological analytical data will be evaluated according to sensitivity, selectivity, accuracy and precision. Different extraction/purification procedures will be described as well as the qualitative-quantitative analyses of volatile and non volatile organic compounds in biological samples.
Students will prove to be able to describe the methodological approach used in forensic genetic analyses for a correct interpretation of DNA identification casework and paternity or kinship cases.
Teaching methods
Frontal lectures
Laboratory case discussion
Reccomended or required readings
1)Tietz Textbook of Clinical Chemistry and Molecular Diagnostics
2)Elisabetta Bertol - ANALITICA TOSSICOLOGICA - Aspetti tecnici, interpretativi, giuridici e deontologici. I Edizione, 2011. Società Editrice Esculapio. Acquistabile on-line al prezzo di euro 23,00
3)Ricci Ugo, Previderè Carlo, Fattorini Paolo, Corradi Fabio -LA PROVA DEL DNA PER LA RICERCA DELLA VERITA' - Giuffrè Ed. 2006
Assessment methods
Written and oral exams
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