DEPARTMENT OF DRUGS SCIENCES
MEDICINAL CHEMISTRY AND PHARMACEUTICAL TECHNOLOGY
2nd semester (02/03/2020 - 19/06/2020)
18 lesson hours
The Neuroscience course is aimed at understanding the main functions and dysfunctions of the nervous system.
Particular attention will be devoted to the relationships between molecular, cellular, and system events, conditions and principles of pharmacological intervention. The course will cover the following aspects.
• Biophysical and biochemical functions of neurons. Mathematical models of neurons and synapses.
• Coding of information in neurons and synapses. Principles of information theory.
• Mechanisms of synaptic plasticity. Induction and expression. Cellular memory foundations.
• Relationship between the cellular properties and behavior: animal models and neural networks. Animal models for the study of nervous system disorders. Circuit and cellular principles of generation of higher functions.
• Consciousness, memory. Attention, motivation, reward. Thought, perception, and motor skills.
• Pathophysiology: main pathologies
• Principles of therapy of nervous system disorders.
Practical exercise: none
Reccomended or required readings
E. D’Angelo, A. Peres, “Fisiologia: Molecole, Cellule e Sistemi”, Vol I-II; EDI-ERMES.
No in itinere tests.
Sustainable development goals - Agenda 2030