2020/2021

2021/2022

DM270

BIO/14 (FARMACOLOGIA)

DIPARTIMENTO DI SCIENZE DEL SISTEMA NERVOSO E DEL COMPORTAMENTO

PSYCHOLOGY, NEUROSCIENCE AND HUMAN SCIENCES

PERCORSO COMUNE

2°

Secondo Semestre (01/02/2022 - 10/06/2022)

6

36 ore di attività frontale

Inglese

SCRITTO E ORALE CONGIUNTI

BLANDINI FABIO (titolare) - 6 CFU

None

The Neuropharmacology teaching course will provide a general view of the mechanisms of action and use of drugs acting on the central nervous system, with specific reference to major conditions and their pharmacological treatment. Students are expected to learn the basic principles of how, where and when a drug can interact with neural systems in a way that will impact on the course or clinical expression of a neurological or psychiatric condition.

The course will include 1) an introductory section, where basic principles of pharmacology, such as pharmacokinetics and pharmacodynamics, along with major concepts regarding synaptic transmission and signal transduction in the brain will be discussed; 2) neural substrates of drug action will be then explained. This will include a description of major neurotransmission systems and transfer of basic concepts of functional neuroanatomy that will provide the basis for the understanding of how drugs acting within the central nervous system can modify the course of neurological or psychiatric disorders; 3) finally, we will discuss how centrally active compounds can impact on different diseases, characterized by relatively high frequency in the general populations - i.e., stroke, epilepsy, Parkinson’s disease, Alzheimer’s disease, migraine, mood disorders, etc. – and what future developments may be expected in the neuropharmacology field.

On-site, frontal lessons (if possible) or on-line lessons, depending on the pandemics evolution in the next months.

Slides used for the lessons will be made available on request

-Goodman & Gilman's. The pharmacological basis of therapy (13th edition)

-Molecular Neuropharmacology: A Foundation for Clinical Neuroscience (4th edition)

Written multiple choice test