Enrollment year
2020/2021
Academic discipline
BIO/14 (PHARMACOLOGY)
Department
DEPARTMENT OF INTERNAL MEDICINE AND THERAPEUTICS
Course
MEDICINE AND SURGERY
Curriculum
PERCORSO COMUNE
Period
2nd semester (03/03/2025 - 06/06/2025)
Lesson hours
8 lesson hours
Activity type
WRITTEN TEST
Prerequisites
General Pharmacology Concepts
In particular, some basic pharmacokinetic concepts will be useful, such as:
Drug absorption: concentration/time curve after oral and intravenous administration, peak plasma concentration, and half-life
Drug distribution: apparent volume of distribution, plasma distribution, distribution in extracellular fluids, and intracellular distribution
Elimination: renal excretion, hepatic metabolism, hepatic cytochromes
Additionally, basic microbiology concepts will be useful:
Gram-positive and Gram-negative bacteria
DNA and RNA viruses
Learning outcomes
The student will be required to know the classification, pharmacokinetics, pharmacodynamics, and main adverse effects of antibacterial, antiviral, and antitumor drugs.
Additionally, the student must demonstrate an understanding of the rational use of antibacterial and antiviral agents to preserve therapeutic potential and minimize the development of drug resistance.
Knowledge of the therapeutic use of the drugs covered, in accordance with the guidelines presented during lectures, will also be required.
Course contents
Part I and II: Antibacterials
Updated guidelines for the treatment of: bacterial meningitis, pneumonia, group B streptococcal pharyngitis, bacterial endocarditis
Beta-lactams (penicillins, cephalosporins, carbapenems, monobactams)
Sulfonamides
Aminoglycosides
Macrolides
Oxazolidinones
Part III: Antivirals
Guidelines for the treatment of viral influenza
Guidelines for the treatment of hepatitis C
Antivirals effective against DNA and RNA viruses
Anti-HBV antivirals
Anti-HCV antivirals
Part IV: Antitumor Drugs
Cytotoxic antitumor agents (alkylating agents, antimetabolites, Vinca alkaloids, cytotoxic antibiotics)
Monoclonal antibodies
Kinase inhibitors
Teaching methods
Lectures will be conducted using PowerPoint presentations projected on a screen, with additional explanations on the blackboard. Practical exercises may be conducted in the classroom to demonstrate the exam format.
Reccomended or required readings
Lecture handouts are available in Italian: Chemotherapy Drugs - Andrea Ferrigno
Other reference texts:
Goodman & Gilman's The Pharmacological Basis of Therapeutics
Rang's Pharmacology
Katzung's Basic & Clinical Pharmacology
Assessment methods
The assessment will be conducted through a 30-minute test consisting of 25 multiple-choice questions.
An oral exam may also be requested.
Further information
To request a meeting, please write to:
andrea.ferrigno@unipv.it
or call:
0382.98.64.51
Sustainable development goals - Agenda 2030
Università di Pavia - Offerta formativa