2019/2020

2020/2021

DM270

BIO/09 (FISIOLOGIA)

DIPARTIMENTO DI MEDICINA MOLECOLARE

MEDICINA E CHIRURGIA (IN LINGUA INGLESE)

PERCORSO COMUNE

2°

Primo Semestre (01/10/2020 - 15/01/2021)

2

16 ore di attività frontale

English

SCRITTO E ORALE CONGIUNTI

PORCELLI SIMONE - 2 CFU

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The course will teach students the phenomena occurring at molecular, cellular, tissue and organ level which support vital functions. At the end of the course, students will know how the organs and systems of the human body work, how their cooperate, and how their function is controlled to keep homeostasis. What is taught at all level of organisation of the living matter will be pout in the frame of the way the organism works. Students will learn the major correlations between the phenomena occurring in physiologic and pathologic conditions.

Organization of the Respiratory System
The Airways and Blood Vessels
Site of Gas Exchange: The Alveoli
Relation of the Lungs to the Thoracic (Chest) Wall
Ventilation and Lung Mechanics
How Is a Stable Balance Achieved Between Breaths?
Inspiration
Expiration
Lung Compliance
Airway Resistance
Lung Volumes and Capacities
Alveolar Ventilation
Exchange of Gases in Alveoli and Tissues
Partial Pressures of Gases
Alveolar Gas Pressures
Gas Exchange Between Alveoli and Blood
Matching of Ventilation and Blood Flow in Alveoli
Gas Exchange Between Tissues and Blood
Transport of Oxygen in Blood
What Is the Effect of PO2 on Hemoglobin Saturation?
Effects of Blood PCO2, H+ Concentration, Temperature, and DPG concentration on Hemoglobin saturation
Transport of Carbon Dioxide in Blood
Transport of Hydrogen Ion Between Tissues and Lungs
Control of Respiration
Neural Generation of Rhythmic Breathing
Control of Ventilation by PO2, PCO2, and H+ Concentration
Control of Ventilation During Exercise
Other ventilatory responses
Hypoxia
Why Do Ventilation–Perfusion Abnormalities Affect O2 More Than CO2?
Emphysema
Acclimatization to High Altitude
Nonrespiratory Functions of the Lungs

Lectures, rehearsal and questions and answers to the class

West's Respiratory Physiology-The Essentials, 10th Edition
Lippincott Williams and Wilkins

Vander's Human Physiology, 14th Edition
McGraw Hill

Ganong's Review of Medical Physiology, 25th Edition
McGraw Hill

Berne & Levy Physiology, 6th Edition
Elsevier

Written text (multiple choices) & oral exam

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