2017/2018

2020/2021

DM270

MED/09 (INTERNAL MEDICINE)

DEPARTMENT OF INTERNAL MEDICINE AND THERAPEUTICS

MEDICINE AND SURGERY

PERCORSO COMUNE

4°

2nd semester (01/03/2021 - 15/06/2021)

1

8 lesson hours

Italian

WRITTEN AND ORAL TEST

NORIS PATRIZIA - 1 ECTS

Knowledge of Molecular and Cellular Biology, Biochemistry, Genetics, Immunology, Anatomy and Histology is required.

The course aims to provide students with the tools necessary to understand the main alterations of the immune response that may be responsible for medical conditions, to recognize and diagnose them by using the appropriate biochemical tools and imaging. The student will be able to recognize the main primary and secondary immunodeficiencies as well as the role of the immune system in transplant rejection and tumor control. Finally, the student will know the principles of treatment of the most important and frequent diseases of the immune system.

Etiology and pathophysiology of hypersensitivity reactions type I, II, III and IV, based on the of the Gell and Coombs classification, and clinical pictures related to them. Classification and grading of primary and secondary immunodeficiencies.
Monoclonal gammopathies: pathophysiology, laboratory and clinical picture. Tumor immunology, mechanisms of escape from immune control, principles of tumor immunotherapy; immunology of solid organ transplantation, immunology of bone marrow transplantation, mechanisms of rejection; adverse drug reactions, allergic and pseudoallergic reactions, pathophysiology and clinical picture.

Teaching sessions supported by slides.

Harrison: Principi di medicina interna. Eds Mc-Graw Hill Companies.

Clinical Immunology/Rheumathology exams are carried out jointly by oral exam. The exam will be conducted by a single teacher with questions on the contents of both courses. The final grade will express the overall evaluation and will represent the grade of the IC of Diseases of the immune system and rheumatology.

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