The course will teach students the phenomena occurring at molecular, cellular, tissue and organ level which support vital functions. At the end of the course, students will know how the organs and systems of the human body work, how their cooperate, and how their function is controlled to keep homeostasis. What is taught at all level of organisation of the living matter will be pout in the frame of the way the organism works. Students will learn the major correlations between the phenomena occurring in physiologic and pathologic conditions.
Structure
Molecular Mechanisms of Skeletal Muscle Contraction
Sliding-Filament Mechanism
Roles of Troponin, Tropomyosin, and calcium in contraction
Excitation–Contraction Coupling
Membrane Excitation: The Neuromuscular Junction
Mechanics of Single-Fiber Contraction
Twitch Contractions
Load–Velocity Relation
Frequency–Tension Relation
Length–Tension Relation
Motor units
Fatigue
Fibre types
Adaptations to exercise
Skeletal Muscle Energy Metabolism
Control of Muscle Tension
Control of Shortening Velocity
Muscle Adaptation to Exercise
Lever Action of Muscles and Bones
Skeletal Muscle Disorders
Muscular Dystrophy
Lectures, rehearsal and questions and answers to the class
One of the following books:
Vander's Human Physiology, 14th Edition - McGraw Hill
Ganong's Review of Medical Physiology, 25th Edition - McGraw Hill
Università di Pavia - Offerta formativa