CHEMISTRY
2014/2015
2014/2015
DM270
BIO/10 (BIOCHIMICA)
DIPARTIMENTO DI MEDICINA MOLECOLARE
MEDICINA E CHIRURGIA (IN LINGUA INGLESE)
PERCORSO COMUNE
PRIMO SEMESTRE (01/09/2014 - 25/09/2014)
5
40 ore di attività frontale
ENGLISH
ORALE
SPEZIALE PIETRO - 3 CFU
VIGLIO SIMONA - 2 CFU
A basic knowledge on General and Organic Chemistry is required.
The aim of the Chemistry course is the knowledge of the chemical structure, the properties and the transformation of the different classes of substances (inorganic and organic) to understand the basic chemical properties and transformation of the molecules in living organisms.
General Chemistry

Elements and compounds. Atoms and molecules (symbolic chemistry; molecular formulas). Mass (mole), energy and electric charge. Periodic system of the elements and electronic configuration; element valence and oxidation state. Interatomic bonds: nature and polarity; molecular shape (structural formulas). Nomenclature of inorganic compounds. Stoichiometry.
Intermolecular bonds. Main characteristics of the solid, liquid and gaseous states. Solutions: solubility; electrolytic dissociation; colligative properties.
Rules of chemical transformations. Spontaneity: thermochemistry, parameters and their significance; chemical equilibrium. Kinetics: reaction rate and order, theory of activated complex; catalysis.
Ionic equilibria in aqueous solutions. Acid–base reactions: water dissociation; pH; theories of acids and bases; neutralization and hydrolysis; amphoteric substances; buffers; variation of the prevailing species with pH.
Oxidations and reductions: spontaneity and redox potential; electrochemical series; electrochemical potential; Nernst equation.

Organic chemistry

Hybridizations of Carbon; molecular geometry; isomerism. Functional groups: nomenclature, structure and reactions. (Aliphatic and aromatic hydrocarbons, alcohols, aldehydes/ketones, amines; carboxylic acids and acylic derivatives; analogues with inorganic groups or with sulfur; heterocycles.)
Frontal lectures.
Katherine J Denniston, Joseph J Topping and Robert L Caret.
General, Organic & Biochemistry.
7th Ed. 2010. McGraw-Hill Higher Education.

J.C. Kotz, P.M. Treichel, J.R. Townsend.
Chemistry and chemical reactivity.
International edition. Brooks/Cole.

J.N. Spencer, G.M. Bodner, L.H. Rickard.
Chemistry: Structure and Dynamics.
4th ed. John Wiley & Sons Inc. Editor.


H. Hart, L.E. Craine, D.J. Hart, C.M. Hadad.
Organic Chemistry. A Short Course.
12th edition. Houghton Mifflin Company; Boston/New York.
Written exam including questions on stechiometry and the theoretical aspects of the general and organic Chemistry.