PHARMACOLOGY B
2010/2011
2014/2015
DM270
BIO/14 (FARMACOLOGIA)
DIPARTIMENTO DI MEDICINA MOLECOLARE
MEDICINA E CHIRURGIA (IN LINGUA INGLESE)
PERCORSO COMUNE
SECONDO SEMESTRE (23/02/2015 - 22/05/2015)
2
16 ore di attività frontale
ENGLISH
ORALE
CREMA FRANCESCA - 1 CFU
RICHELMI PLINIO - 1 CFU
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By the end of the course students will be expected to:

a) describe and interpret drug-induced therapeutic and adverse effects on the various organs and systems;

b) assess the risk/benefit ratio of drugs under different conditions of therapeutic usage;

c) correctly select and use drugs for the treatment of major diseases.
1. Pharmacology

a. cardiovascular pharmacology

antianginals; antihypertensives; cardioactive glycosides and other positive inotropic drugs;

antiarrhythmics; antidyslipemics; anticoagulants; thrombolytics; anitplatelet drugs;

diuretics; drugs for haematological disorders.

b. endocrine and metabolic pharmacology

pituitary hormones; thyroid hormones and antithyroid drugs; adrenocortical hormones;

antidiabetics; androgens, estrogens, progestagens and combination products;

other contraceptive agents; agents affecting calcium homeostasis;

drugs for the treatment of osteoporosis; vitamins.

c. autonomic pharmacology

drugs of the adrenergic and cholinergic systems.

d. gastro-intestinal pharmacology

antiulcer drugs, prokinetics, laxatives, antidiarrhoeics, antiemetics.

e. respiratory pharmacology

antiasthmatics.

f. genitourinary pharmacology

drugs affecting uterine motility; drugs for the treatment of prostatic hypertrophy.

g. immunopharmacology and pharmacology of inflammation

immunomodulators and immunosuppressants; antihistamines; nonsteroidal anti-inflammatory drugs; corticosteroids and other drugs for the treatment of rheumatoid arthritis;

antigout drugs; antipyretics.

2. Neuropsychopharmacology

antipsychotics; antidepressants; anxiolytics; hypnotics; major analgesics;

antiepileptic drugs; antiparkinson drugs; antimigraine drugs; muscle relaxants; general and local anaesthetics; drugs used for the treatment of dementia and of neurodegenerative disorders.

3. Chemotherapy

beta-lactam antibiotics; aminoglycosides; quinolones; macrolides; lincosamides; glycopeptides; tetracyclines; chloramphenicol; sulphonamides; riphamycines; drugs for the treatment of tuberculosis and other mycobacterial infections; antimycotics; antivirals;

antiprotozoal agents; anti-helmintics; antineoplastic agents.

4. Toxicology

Organ and system toxicity (liver, kidney, nervous system, respiratory system, reproductive system); alcoholism and alcohol-related disorders; acute intoxications (toxic gases, mushrooms, agricultural products, household chemicals, psychoactive drugs; diagnostic and therapeutic management); toxicological risks during pregnancy; poisoning occurring in special situations (paediatric and old age); drug abuse and addiction; toxic effects of environmental contaminants.
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Recommended Textbooks (please use the most recent edition):

Goodman & Gilman’s : The Pharmacological Basis of Therapeutics, McGraw-Hill.
Katzung B.G.: Basic and Clinical Pharmacology, McGraw-Hill.
Fulgraff G.: Farmacologia e Terapia Clinica, Edizioni Mediche Scientifiche Internazionali.
Annunziato L., Di Renzo G.: Trattato di Farmacologia, Ed. Idelson Gnocchi.
The Pharmacology II examination consists of an oral test. In itinere evaluations may be conducted as a written test.